As a minor update, iTunes 10.4.1 only features some minor bug fixes such as addressing issues with adding artwork to songs and videos, fixes a problem where the media keys on some third-party keyboards work inconsistently with iTunes, resolves an issue which may cause iTunes to become unresponsive when purchasing an HD movie, and obviously to address issues with VoiceOver support.
You can simply download it via iTunes Update menu or alternatively you can also download iTunes 10.4.1 standalone setup installer file for Windows 32-bit, Windows 64-bit as well as Mac OS X flavor.
Official Direct Download Links for Windows 32-bit
File Name : iTunesSetup.exe
Download iTunes 10.4.1 .exe for Windows 32-bit
File Name : iTunes64Setup.exe
Download iTunes 10.4.1 .exe for Windows 64-bit
File Name : iTunes10.4.1.dmg
Download iTunes 10.4.1 .dmg for Mac OS X